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ERITHACUS SOFTWARE LIMITED computer software graphite
Computer Software Graphite, supplied by ERITHACUS SOFTWARE LIMITED, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/graphit+computer+software/computer+software+graphite/pm11035072-78-19-29
Average 90 stars, based on 1 article reviews
computer software graphite - by Bioz Stars, 2026-09
90/100 stars

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Article Title: In vivo and in vitro ADMET profiling and in vivo pharmacodynamic investigations of a selective α7 nicotinic acetylcholine receptor agonist with a spirocyclic Δ 2 -isoxazoline molecular skeleton.
Article Snippet: ±)-3-Methoxy-1-oxa-2,7-diaza-7,10-ethanospiro[4.5]dec-2-ene sesquifumarate (±)-1 was previously characterized as the most selective agonist at α7 neuronal nicotinic acetylcholine receptors in a series of spirocyclic quinuclidinyl-Δ-isoxazoline derivatives.. In this study, we performed different in vitro biological assays aimed at characterizing the ADMET properties of (±)1.. Then, we tested the compound in vivo in behavioral studies including classical novel object recognition and inhibitory avoidance tests in the rat, and a spatial memory assay in zebrafish involving a rapid T-maze task.

Article Title: Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads.
Article Snippet: 0960-894X/$ see front matter 2012 Elsevier Ltd. doi:10.1016/j.bmcl.2011.12.071 ⇑ Corresponding author.. Tel.. : +44 1782 724371.

Article Title: Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
Article Snippet: The IC 50-values were calculated using Graphit 4.0.15 (Erithacus Software, Ltd., UK).

Article Title: Functional roles of the pre-sensor I insertion sequence in an AAA+ bacterial enhancer binding protein
Article Snippet: V max and K m values as well as standard errors were determined at initial concentrations of 0.05–1 mM ATP using non-linear regression Graphit software (Erithacus Software Limited).

Article Title: Molecular Insights into the Biosynthesis of the F 420 Coenzyme
Article Snippet: Data were collected at least in triplicate for each ligand, and curve fitting of the data was performed by using Graphit 4.0.10 (Erithacus Software) as described previously ( 34 ).

Article Title: Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
Article Snippet: The Ki-values were calculated using Graphit 4.0.15 (Erithacus Software, Ltd., UK) and were determined as Ki=8.52*10−5 M±6.33*10−6 M for glutaminyl pyrrolidine and Ki=1.07*10−5 M±3.81*1031 7 M for glutaminyl thiazolidine.

Article Title: Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
Article Snippet: The Ki-values were calculated using Graphit 4.0.15 (Erithacus Software, Ltd., UK) and were determined as Ki=8.52*10−5 M±6.33*10−6 M for glutaminylpyrrolidine and Ki=1.07*10−5 M±3.81*10−7M for glutaminylthazolidine.

Software:

Article Title: Mechanism of homotropic control to coordinate hydrolysis in a hexameric AAA+ ring ATPase.
Article Snippet: 0022-2836/$ see front matter © 2008 E AAA proteins are ubiquitous mechanochemical ATPases that use energy from ATP hydrolysis to remodel their versatile substrates.. The AAA characteristic hexameric ring assemblies raise important questions about if and how six often identical subunits coordinate hydrolysis and associated motions.. The PspF AAA domain, PspF1–275, remodels the bacterial σ – RNA polymerase to activate transcription.



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